Nonalcoholic Steatohepatitis (NASH) Fat buildup in the liver that is not alcohol related is called nonalcoholic fatty liver disease (NAFLD). This causes swelling and, eventually, cirrhosis. Heavy Alcohol Use Alcohol is toxic to the liver, and drinking too much can lead to inflammation of the liver and changes in the liver cells themselves. Although it’s less common, hepatitis B and D can also cause cirrhosis.
It causes the liver to swell, which can eventually lead to cirrhosis.Ībout 1 in 4 people with hepatitis C develop cirrhosis. Cirrhosis is stage 4, or the last stage of scarring of the liver, she says.Ĭhronic Viral Hepatitis B, C, or D Chronic hepatitis C is the leading cause of cirrhosis in the United States. “There are actually four different stages of scarring: F1 (minimal scarring), F2 (significant scarring), F3 (severe fibrosis), and F4 (advanced scarring),” says Dr. Scarring, or fibrosis, in the liver occurs when it is exposed to toxic substances - such as alcohol or other drugs - or to inflammation, which can be caused by any liver disease, says Christina Lindenmeyer, MD, a gastroenterologist at the Cleveland Clinic in Ohio. If cirrhosis goes untreated, the liver will not be able to function well and liver failure may result. Over time, the scar tissue inhibits the flow of blood through the liver and impairs the ability of the liver to process nutrients, hormones, and medication.Ĭirrhosis is always related to other liver diseases and commonly develops from chronic hepatitis, alcohol-related liver disease (ARLD), or nonalcoholic fatty liver disease (NAFLD). Chronic liver disease can lead to cirrhosis, a condition in which the healthy tissue in the liver is replaced by nonliving scar tissue.
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